Transhumance in the Early Neolithic? Carbon and oxygen isotope insights into sheep husbandry at Arene Candide, Northern Italy

Theoretical insights into the encapsulation of anticancer Oxaliplatin drug into single walled carbon nanotubes

The present work was an attempt to evaluate the potentialities of using SWCNTs as nanovectors for drug delivery of anticancer drug Oxaliplatin. First-principles van der Waals density functional (vdW-DF) calculations are used to investigate the incorporation of oxaliplatin inside the typical semiconducting and metallic single wall carbon nanotubes with various diameters (SWCNTs). Adsorption ener...

Sulfur and oxygen isotope insights into sulfur cycling in shallow-sea hydrothermal vents, Milos, Greece

Shallow-sea (5 m depth) hydrothermal venting off Milos Island provides an ideal opportunity to target transitions between igneous abiogenic sulfide inputs and biogenic sulfide production during microbial sulfate reduction. Seafloor vent features include large (>1 m(2)) white patches containing hydrothermal minerals (elemental sulfur and orange/yellow patches of arsenic-sulfides) and cells of su...

Structural insights into the effects of charge-reversal substitutions at the surface of horseradish peroxidase

Horseradish peroxidase (HRP), has gained significant interests in biotechnology, especially in biosensor field and diagnostic test kits. Hence, its solvent-exposed lysine residues 174, 232, and 241 have been frequently modified with the aim of improving its stability and catalytic efficiency. In this computational study, we investigated the effects of Lys-to-Glu substitutions on HRP structure t...

MAVEN insights into oxygen pickup ions at Mars

Since Mars Atmosphere and Volatile EvolutioN (MAVEN)’s arrival at Mars on 21 September 2014, the SEP (Solar Energetic Particle) instrument on board the MAVEN spacecraft has been detecting oxygen pickup ions with energies of a few tens of keV up to ~200 keV. These ions are created in the distant upstream part of the hot atomic oxygen exosphere of Mars, via photoionization, charge exchange with s...

Paired positive carbonate carbon isotope, organic carbon isotope, and oxygen isotope composition study across the Lower Mississippian positive carbon isotope excursion, southeastern Nevada, USA